Fifth Avenue’s distinctive Flatiron Building lends its name to the surrounding Flatiron District, which is defined by its mix of beaux-arts and cast-iron architecture and the inviting greenery of Madison Square Park. Also noteworthy: an ever-expanding dining scene led by an impressive roster of notable chefs preparing a diverse range of cuisines. Get a taste of the Flatiron’s best dining options during Restaurant Week. 

Combining culinary influences from Long Island’s Montauk and New Orleans, the kitchen at Bo’s turns out soulful, flavorful dishes like lemon-buttermilk fried chicken, vegetable coconut curry and fried cookie dough for dessert. At the bar, sample tempting snacks and a lengthy seasonal cocktail list while enjoying weekly live music performances and a monthly reading series. 

British Michelin-starred chef and Gordon Ramsay Group alum Jason Atherton helms this sophisticated venture in the New York Edition hotel. The dishes—like 40-day dry-aged strip steak, butter-roasted Dover sole, Hudson Valley foie gras—mirror the elegance of the restaurant’s 24-karat gold leaf bar.

The flashiness of NYC’s storied Limelight club lives on at Jue Lan Club, which has taken over the historic church space on West 20th street. Velvet booths and chandeliers replace spotlights and dance floors while crowd-pleasing Asian-fusion dishes like bao buns, General Tso’s chicken dumplings and lobster fried rice take center stage. 

Diners looking to sample Indian cuisine beyond a simple chicken tikka should venture into this palatial dining room, adorned with a reflecting pool and carved archways. With plates like tandoori octopus and crispy lotus root, the Michelin-starred restaurant brings a modern flair to traditional Indian flavors.

Flown in from Italy twice a week, the fresh mozzarella—pillowy burrata, naturally smoked bufala—is the headliner at this sleek Flatiron outpost of Obicà’s international brand. Sample the cheeses on their own, or pair them with a variety of antipasti, pizzas and pastas. 

Since opening in 1987, Periyali has blended white-tablecloth finesse with rustic Greek cuisine. The whitewashed decor and the kitchen’s impeccably executed dishes (rabbit stew, moussaka, grilled branzino) evoke beachside dining in Mykonos. 

Equal parts pisco lounge, ceviche bar and Peruvian kitchen, Raymi’s colorful space represents Peru’s vibrant mix of Japanese, Chinese and Spanish-influenced flavors. Sip a pisco sour while sampling creative ceviches and entrees, or opt for the indulgent, family-style suckling pig dinner. 

Fans of authentic Italian eats may be acquainted with the original Zero Otto Nove on Arthur Avenue, within the Bronx’s Little Italy. Robert Paciullo, a native of Salerno, Italy, brings the same Southern Italian flavors—via Neapolitan pizzas and hearty pastas—to this airy, stucco-walled space on West 21st Street.